Boronic acid, (4-hydroxy-2-methylphenyl)- (9CI)

Boronic acid, (4-hydroxy-2-methylphenyl)- (9CI) - Names and Identifiers

Name	4-Hydroxy-2-methyl phenyl boronic acid
Synonyms	4-Borono-3-methylphenol 5-hydroxytoluene-2-boronic acid 4-Hydroxy-2-methylphenylboronic aicd 4-Hydroxy-2-methylbenzeneboronic acid 4-Hydroxy-2-methyl phenyl boronic acid (4-Hydroxy-2-methylphenyl)boronic acid (4-Hydroxy-2-methyl)phenylboronic acid (4-HYDROXY-2-METHYL)PHENYLBORONIC ACID (4-HYDROXY-2-METHYL)BENZENEBORONIC ACID BORONIC ACID,B-(4-HYDROXY-2-METHYLPHENYL)- boronic acid, B-(4-hydroxy-2-methylphenyl)- Boronic acid, (4-hydroxy-2-methylphenyl)- (9CI) 4-Borono-3-methylphenol, 2-Borono-5-hydroxytoluene
CAS	493035-82-8
InChI	InChI=1/C7H9BO3/c1-5-4-6(9)2-3-7(5)8(10)11/h2-4,9-11H,1H3

Boronic acid, (4-hydroxy-2-methylphenyl)- (9CI) - Physico-chemical Properties

Molecular Formula	C7H9BO3
Molar Mass	151.96
Density	1.26±0.1 g/cm3(Predicted)
Melting Point	100-104°C
Boling Point	361.4±52.0 °C(Predicted)
Flash Point	172.4°C
Vapor Presure	7.43E-06mmHg at 25°C
pKa	9.17±0.58(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.569

Boronic acid, (4-hydroxy-2-methylphenyl)- (9CI) - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S39 - Wear eye / face protection.
Hazard Class	IRRITANT

Boronic acid, (4-hydroxy-2-methylphenyl)- (9CI) - Introduction

4-Hydroxy-2-methyl phenyl boronic acid is an organic boron compound with the chemical formula C7H9BO3.

Nature:
-Appearance: White crystalline solid
-Solubility: Soluble in alcohols and some organic solvents, slightly soluble in water
-melting point: about 170-173 ℃

Use:
-It is an important derivative of aromatic compounds and is often used as an intermediate in organic synthesis.
-Due to its reactivity with other compounds, it can be used to synthesize anti-cancer drugs, pesticides, photosensitive materials and coordination compounds.

Preparation Method:
4-Hydroxy-2-methyl phenyl boronic acid has various preparation methods, and the common ones are as follows:
-can be obtained by the hydroxyl etherification reaction of p-methylphenylboronic acid. The specific reaction steps include reacting methylbenzeneboronic acid with hydroquinone under alkaline conditions to produce 4-Hydroxy-2-methyl phenyl boronic acid.
-It can also be obtained by the alkylation reaction of p-methylphenylboronic acid. The specific reaction steps include reacting methylphenylboronic acid with iodane under alkaline conditions to produce 4-Hydroxy-2-methylphenyl boronic acid.

Safety Information:
4-Hydroxy-2-methyl phenyl boronic acid is a relatively safe compound under general use conditions, but the following matters still need to be paid attention:
-During use, wear protective gloves and protective glasses to prevent contact with skin and eyes.
-Avoid inhaling its dust or gas and avoid ingestion.
-During storage, it is necessary to keep dry and avoid contact with oxidants and other substances.
-In case of swallowing, entering eyes or skin contact, rinse immediately with water and seek medical help.

Last Update：2024-04-09 15:17:58